ISRAEL DAVID GOLDMAN, MD

Unless otherwise indicated, this information has been self-reported and has not been verified by the Board of Medicine.

University Of North Carolina At Chapel Hill School Of Medicine - Chapel Hill NC
Rank: Assistant/Associate Professor
Years: 1969-1974

Virginia Commonwealth University School Of Medicine (Previously MCV) - Richmond VA
Rank: Associate/Full Professor
Years: 1974-1995

Albert Einstein College Of Medicine Of Yeshiva University - Bronx NY
Rank: Full Professor
Years: 1995-Present

None Reported

Identification of an Extracellular Gate for the Proton-coupled Folate Transporter (PCFT-SLC46A1) by Cysteine Cross-linking.
J. Biol. Chem.
Volume: 291
Date: 04 2016
https://www.ncbi.nlm.nih.gov/pubmed/26884338

The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption.
Mol Aspects Med. 2017
Volume: 53
Date: 02 2017
https://www.ncbi.nlm.nih.gov/pubmed/27664775

Hereditary Folate Malabsorption
Gene Reviews
Date: 04 2017
https://pubmed.ncbi.nlm.nih.gov/20301716/

Impact of posttranslational modifications of engineered cysteines on the substituted cysteine accessibility method: evidence for glutathionylation.
Am J Physiol Cell Physiol.
Volume: 312
Date: 04 2017
https://www.ncbi.nlm.nih.gov/pubmed/28122733

Residues in the eighth transmembrane domain of the proton-coupled folate transporter (SLC46A1) play an important role in defining the aqueous translocation pathway and in folate substrate binding.
Biochim Biophys Acta Biomembr. 2017 Nov;1859(11):
Volume: 1859
Date: 11 2017
https://www.ncbi.nlm.nih.gov/pubmed/28802835

The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption.
Mol Aspects Med. 2017 Feb;53:
302(9):C1405-12. 22345511
Date: 01 2018

Hereditary folate malabsorption due to a mutation in the external gate of the proton-coupled folate transporter SLC46A1. Blood Adv. 2018 Jan 5;2(1):61-68. doi:
Blood Advances
2(1):61-68, 2018
Date: 02 2018
https://www.ncbi.nlm.nih.gov/pubmed/29344585

Substituted-cysteine accessibility and cross-linking identify an exofacial cleft in the 7th and 8th helices of the proton-coupled folate transporter (SLC46A1).
Am J of Physiol.Cell Physil
Volume: 314
Date: 03 2018
https://www.ncbi.nlm.nih.gov/pubmed/29167151

Substitutions that lock and unlock the proton-coupled folate transporter (PCFT-SLC46A1) in an inward-open conformation
Journal of Biological Chemistry
Volume: 292
Date: 05 2019
https://pubmed.ncbi.nlm.nih.gov/30858177/

A proton-coupled folate transporter mutation causing hereditary folate malabsorption locks the protein in an inward-open conformation
Journal of Biological Chemistry
Volume: 295
Date: 11 2020
https://pubmed.ncbi.nlm.nih.gov/32893190/